EGFRKRASTP53BRCA1HER2VEGFRCDK4/6PD-L1PARPBCR-ABLmTORALKBRAFRETMETEGFRKRASTP53BRCA1HER2VEGFRCDK4/6PD-L1PARPBCR-ABLmTORALKBRAFRETMET
AI-Native Drug Repurposing

The cure
was already
there.

Metformin sat in medicine cabinets for 50 years before anyone tried it on cancer. Helix surfaces those discoveries in minutes — not decades.

~$1B
Cost of new drug development
10–15yr
Traditional approval timeline
<4min
Helix analysis time
9,000+
FDA-approved drugs to mine
— The Pipeline

One input.
Full research
pipeline.

01
Literature Synthesis
AI agents crawl arXiv and deep research databases to build a current knowledge base for your target cancer type.
02
Target Identification
High-impact proteins like EGFR, KRAS, and p53 are extracted with known mechanisms and FDA status.
03
Structure Retrieval
High-resolution protein structures fetched from RCSB. Compounds sourced from PubChem and canonicalized.
04
GPU Docking Simulation
DiffDock runs on Nvidia Blackwell GPUs — physics-informed diffusion modeling ranks binding confidence across all candidates.
05
Ranked Report
Repurposing candidates surface with confidence scores, mechanisms, and a shareable research report.
Helix © 2025AI-native drug repurposing